Serotonin syndrome can occur when antiemetics like ondansetron are taken with SSRIs or other serotonergic drugs. Learn the signs, risks, and how to prevent this rare but dangerous reaction.
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Despite a 2006 FDA warning, combining triptans and SSRIs does not significantly increase the risk of serotonin syndrome. Evidence from large studies and expert consensus confirms the combination is safe for migraine patients on antidepressants.
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